The symptoms of Sjögren’s Syndrome vary greatly between individuals.
Symptoms include a dryness of the moist areas of the body, like the mouth, eyes, ears, nose and vagina. Fatigue and depression, plus painful joints, are also associated with the disease.
When organs other than the lacrimal and salivary glands are affected, this is known as “extraglandular involvement.” Usually, this occurs in patients with primary Sjögren’s syndrome (see “Primary Versus Secondary Sjögren’s Syndrome”).
Manifestations of Primary Sjögren’s Syndrome include :
- joint inflammation
- particular forms of autoimmune thyroid, kidney, liver, lung, and skin disease
- changes in nerve function of the upper or lower limbs
- small proportion of patients may progress to a form of lymphoma
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RESOURCE: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)